BROOKLYN, NY. — A new clinical trial has shown that Kingdom Supercultures’ novel postbiotic ingredient, Superculture® Pet Oral, can help address bad breath in canines by impacting oral microbiome function.
Oral health in pets has grown in importance as dental disease continues to be a common issue in dogs. It’s estimated that more than 80% of dogs over the age of three have active dental disease. One of the ways to help address this health issue is by reducing bad breath, thereby supporting the overall oral microbiome. Kingdom Supercultures’ ingredient seeks to accomplish this by targeting specific pathogenic microbes in the mouth that produce volatile sulfur compounds (VSC) and cause bad breath associated with poor oral health.
Kingdom Supercultures’ Superculture® Pet Oral ingredient contains dried Pediococcus pentosaceus (a lactic acid bacteria), dried Bacillus subtilis and a tapioca maltodextrin carrier. The bacteria are heat treated to inactivate the live cells and then spray or freeze dried into a powdered topper.
The company conducted a double-blind, placebo-controlled, randomized trial to evaluate the efficacy of Superculture® Pet Oral. The 14-day trial included 24 dogs separated into two groups. Before the study began, the dogs underwent a five-day acclimation period in which they didn’t receive any oral health treatments or products.
From days one to 14, one group was fed 250 mgs of the postbiotic and the other was fed a placebo in addition to a dry dog food. Following feeding, a technician performed breath sampling measurements and recorded each dog’s breath score on days zero, seven and 14.
According to the results, by day seven Superculture® Pet Oral was found to significantly decrease the baseline of VCS by 22%. In the placebo group, VCS increased 35% over the course of the trial. Throughout the entire trial, the postbiotic lowered VSC levels by 27% compared to the placebo and prevented an increase in VCS. Twice as many dogs fed the postbiotic had perceptibly improved breath on day seven compared to those fed the placebo.
Additionally, the researchers compared the results of the trial to other clinical trials on traditional dental chews, finding that Kingdom Supercultures’ ingredient was about twice as effective.
“These findings validate the ability of this novel postbiotic to effectively reduce canine oral malodor and provide preliminary evidence that it may more broadly help to maintain canine oral health,” the researchers wrote.
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